Category Archives: Research

Congratulations to CureSearch Young Investigator Dr.Yustein

New Ewing Sarcoma Research Center at Texas Children’s Hospital Made Possible by Virani Family This article features CureSearch Young Investigator Jason Yustein, MD, PhD. To learn more about his research click here. (Bio News Texas) -The Texas Children’s Cancer Center has opened a new space to develop more effective diagnostics and therapeutic approaches for Ewing Sarcoma […]

New Promising Information to Treat, Cure Childhood Leukemias

(Science World Report) – Researchers from the UT Health Center may have pinpointed a protein that could potentially play a key role in the development of pediatric AML-promising new information to treat and cure possible childhood leukemias. Background information from the study notes that AML begins when maturing cells start to grow into different kinds […]

Researcher Studies Hepatocellular Carcinoma

Research Aimed at Understanding Mechanistic Characterization of Tumor Initiating Cells Liver cancer is rare in children and adolescents. There are two main types of childhood liver cancer: hepatoblastoma, a very rare kind of liver cancer usually found in children under 4; and hepatocellular carcinoma (HCC), the most common type of liver cancer in adolescents, young […]

Researcher Examines the Body’s Immune System in Search of Treatments for Osteosarcoma

Osteosarcoma is a primary bone cancer affecting approximately 400 children and adolescents in the United States each year. Current treatment for this cancer is usually extensive surgery followed by chemotherapy. Even with aggressive treatment, the survival rate is just 60-70%. Further, about 40% of patients with osteosarcoma experience metastatic (cancer that has spread) or recurrent disease. For […]

Researcher Examines Impact of Extra Chromosome on Acute Myeloid Leukemia

Human cells are made of many parts, including chromosomes which are organized structures of DNA. Their job is to help direct the actions of various types of cells. There are 23 chromosomes and normally, each cell contains 2 copies of each chromosome for a total of 46 chromosomes. Scientists have long known that many types of […]

CureSearch Awards $1.2 Million in Grants

CureSearch for Children’s Cancer has awarded $1.2 million in clinical trials support to 77 hospitals who applied for Clinical Trials Advancement Awards. All hopsitals who applied for grants received funding for enrolling infants, children, adolescents, and young adults in Phase I, Phase II, and Phase III therapeutic clinical trials. Clinical Trials Advancement Awards range from […]

Developing CD47 Antibody Therapy for Children’s Cancer

A research team at Stanford University led by Drs. Kathleen Sakamoto and Irv Weissman has received a $1.37 million grant from CureSearch titled “Development of CD47 Monoclonal Antibody Therapy for Pediatric Tumors.” In a healthy person, when the body makes abnormal cells or cells become old, the body’s scavenger cells, called macrophages, eliminate them in […]