For Immediate Release
April 23, 2012
Erica Neufeld
(240) 235-2201 

Research Grants Announced for 12 Areas of Children's Cancer

CureSearch for Children's Cancer Announces Young Investigator Awards in Disease Areas Representing the Highest Risk and Poorest Outcomes for Children with Cancer

Bethesda, MD – CureSearch for Children's Cancer today announced 12 $100,000 grants for scientists focused on innovative research offering the greatest potential to design treatments and improve outcomes for children with difficult-to-treat cancers.

Working with a panel of children's cancer research experts, CureSearch identified 12 areas of study that present the highest risk with the poorest outcomes for children with cancer. "We recognize that for many types of children's cancer, survival rates have not significantly increased in the past two decades," said Stuart Siegel, MD who is Chair of the CureSearch Board of Directors and Director of the Children's Center for Cancer and Blood Diseases at Children's Hospital Los Angeles. "By strategically placing funds in the hands of researchers focused on these cancers, we hope to help move the needle so that more children have a chance for a cure."

With the advent of new scientific advances -- genomics, proteomics, targeted therapies, experimental therapeutics, biomarkers, and functional testing -- scientists are now equipped to advance research at a pace faster than ever. Recognizing the tremendous opportunities these new scientific approaches present, CureSearch seeks Young Investigators who are applying these advances to the field of children's cancer research in the following areas:

  • Relapsed acute lymphoblastic leukemia
  • Acute myeloid leukemia
  • Brain tumors (including studies of the blood brain barrier)
  • Bone tumors (Ewing sarcoma, osteosarcoma, etc.)
  • Liver tumors
  • Large cell lymphomas
  • Neuroblastoma
  • Rare tumors (retinoblastoma, germ cell, melanoma, thyroid, etc.)
  • Kidney tumors (high-risk Wilm's tumor, renal cell carcinoma, etc.)
  • Rhabdomyosarcoma and other soft tissue tumors (e.g., fibrosarcoma)
  • Adolescent and young adult cancers
  • Survivorship, wellness, and late effects

By focusing on research in these areas whose outcomes have the potential to turn into clinical trials that will one day be available through the Children's Oncology Group or other collaborative clinical trials networks, CureSearch hopes to help speed the transition from scientific advancement to treatment.

CureSearch will fund at least one Young Investigator in each of the above disciplines every year beginning in 2012. Awards of $100,000 over two years will be provided, with the possibility of extension.  In addition, each researcher will be assigned to a mentor-of-distinction; an expert in their field of research who will closely follow the activities and results of the research project to ensure that the investigator is employing the most cutting-edge applications and has a high degree of extramural connectivity to facilitate an active and growing culture of dialogue between basic science research and clinical trial design.

For those interested in applying, initial RFPs will be posted on Proposal Central in mid-May, with additional postings throughout 2012.

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CureSearch Investigational Research Initiative
The CureSearch Investigational Research Initiative was created to advance children's cancer research by investing in transformational science aimed at delivering the next generation of treatments.

CureSearch for Children's Cancer
CureSearch for Children's Cancer is a national non-profit foundation whose mission is to fund and support children's cancer research and provide information and resources to all those affected by children's cancer. CureSearch raises funds for promising research conducted at more than 175 hospitals in the United States, participating in National Cancer Institute sponsored clinical trials conducted by the Children's Oncology Group. CureSearch also funds other clinical, basic and translational research so that researchers can understand all aspects of children's cancer, from its causes to its consequences.

Christine Bork
Email Christine
(800) 458-6223

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